Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | set01_ATM_minus_versus_ATM_plus |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | NCI_IL2-MEDIATED SIGNALING EVENTS |
| Enrichment Score (ES) | -0.59511733 |
| Normalized Enrichment Score (NES) | -2.3600612 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RAN | 122 | 13.946 | 0.0167 | No | ||
| 2 | HRAS | 510 | 8.966 | 0.0134 | No | ||
| 3 | MYC | 869 | 7.330 | 0.0087 | No | ||
| 4 | XPO1 | 1342 | 5.926 | -0.0034 | No | ||
| 5 | E2F1 | 1414 | 5.788 | 0.0026 | No | ||
| 6 | MAPK1 | 1423 | 5.768 | 0.0115 | No | ||
| 7 | IL2RB | 1434 | 5.742 | 0.0202 | No | ||
| 8 | UBE2D3 | 2039 | 4.762 | 0.0002 | No | ||
| 9 | MAPKAPK2 | 2720 | 3.998 | -0.0245 | No | ||
| 10 | CCNA2 | 3305 | 3.575 | -0.0456 | No | ||
| 11 | KRAS | 3504 | 3.433 | -0.0491 | No | ||
| 12 | IL2RA | 3564 | 3.387 | -0.0464 | No | ||
| 13 | PPP2R5D | 4047 | 3.115 | -0.0635 | No | ||
| 14 | SMPD1 | 5130 | 2.677 | -0.1087 | No | ||
| 15 | SOS1 | 5789 | 2.466 | -0.1349 | No | ||
| 16 | PIK3R1 | 6230 | 2.327 | -0.1513 | No | ||
| 17 | IFNG | 6243 | 2.320 | -0.1482 | No | ||
| 18 | SOCS3 | 6520 | 2.246 | -0.1572 | No | ||
| 19 | RAC1 | 7002 | 2.119 | -0.1759 | No | ||
| 20 | NFKB1 | 7091 | 2.093 | -0.1765 | No | ||
| 21 | FASLG | 7259 | 2.047 | -0.1809 | No | ||
| 22 | GAB2 | 7726 | 1.924 | -0.1992 | No | ||
| 23 | TERT | 7911 | 1.880 | -0.2046 | No | ||
| 24 | CDK6 | 8138 | 1.830 | -0.2120 | No | ||
| 25 | CALM1 | 10454 | 1.273 | -0.3160 | No | ||
| 26 | PRKCZ | 10572 | 1.242 | -0.3193 | No | ||
| 27 | CDK2 | 10991 | 1.139 | -0.3366 | No | ||
| 28 | RPS6 | 11187 | 1.089 | -0.3438 | No | ||
| 29 | CALM2 | 11871 | 0.882 | -0.3737 | No | ||
| 30 | IL4 | 12402 | 0.724 | -0.3968 | No | ||
| 31 | JUN | 12565 | 0.666 | -0.4031 | No | ||
| 32 | REL | 14913 | -0.486 | -0.5098 | No | ||
| 33 | SRC | 15241 | -0.705 | -0.5237 | No | ||
| 34 | GRB2 | 15610 | -0.952 | -0.5390 | No | ||
| 35 | IRS1 | 15669 | -0.991 | -0.5401 | No | ||
| 36 | MAP2K1 | 15741 | -1.040 | -0.5417 | No | ||
| 37 | TNF | 16079 | -1.307 | -0.5550 | No | ||
| 38 | RIPK2 | 16143 | -1.360 | -0.5557 | No | ||
| 39 | SHC1 | 16723 | -1.857 | -0.5792 | No | ||
| 40 | TRAF6 | 16980 | -2.105 | -0.5876 | No | ||
| 41 | AKT1 | 17066 | -2.193 | -0.5880 | No | ||
| 42 | RHOA | 17075 | -2.199 | -0.5848 | No | ||
| 43 | MAPK9 | 17214 | -2.310 | -0.5874 | No | ||
| 44 | ERC1 | 17266 | -2.356 | -0.5860 | No | ||
| 45 | CALM3 | 17354 | -2.438 | -0.5861 | No | ||
| 46 | MAP3K14 | 17377 | -2.462 | -0.5831 | No | ||
| 47 | FOXP3 | 17466 | -2.555 | -0.5831 | No | ||
| 48 | CHUK | 17643 | -2.730 | -0.5868 | No | ||
| 49 | MAPK14 | 17811 | -2.903 | -0.5898 | No | ||
| 50 | JAK3 | 17929 | -3.030 | -0.5903 | Yes | ||
| 51 | MAPK3 | 17962 | -3.067 | -0.5868 | Yes | ||
| 52 | MAPK11 | 18040 | -3.143 | -0.5853 | Yes | ||
| 53 | SOCS2 | 18085 | -3.196 | -0.5822 | Yes | ||
| 54 | BCL3 | 18305 | -3.430 | -0.5867 | Yes | ||
| 55 | IKBKG | 18397 | -3.530 | -0.5853 | Yes | ||
| 56 | SYK | 18493 | -3.653 | -0.5838 | Yes | ||
| 57 | PTPN11 | 18707 | -3.890 | -0.5873 | Yes | ||
| 58 | ATM | 18851 | -4.077 | -0.5873 | Yes | ||
| 59 | STAM | 18942 | -4.204 | -0.5847 | Yes | ||
| 60 | PRKCA | 18987 | -4.255 | -0.5799 | Yes | ||
| 61 | ARRB2 | 19063 | -4.371 | -0.5763 | Yes | ||
| 62 | RAF1 | 19074 | -4.383 | -0.5698 | Yes | ||
| 63 | FOS | 19178 | -4.546 | -0.5672 | Yes | ||
| 64 | IRS2 | 19314 | -4.756 | -0.5658 | Yes | ||
| 65 | LTA | 19451 | -4.972 | -0.5640 | Yes | ||
| 66 | NFKB2 | 19492 | -5.020 | -0.5578 | Yes | ||
| 67 | BIRC2 | 19566 | -5.145 | -0.5529 | Yes | ||
| 68 | STAT5A | 19672 | -5.285 | -0.5493 | Yes | ||
| 69 | JAK1 | 19675 | -5.293 | -0.5409 | Yes | ||
| 70 | IKBKB | 19718 | -5.359 | -0.5343 | Yes | ||
| 71 | CYLD | 19870 | -5.610 | -0.5322 | Yes | ||
| 72 | PRF1 | 19877 | -5.627 | -0.5234 | Yes | ||
| 73 | BCL10 | 20231 | -6.352 | -0.5294 | Yes | ||
| 74 | MAP2K2 | 20359 | -6.618 | -0.5247 | Yes | ||
| 75 | RELB | 20410 | -6.758 | -0.5161 | Yes | ||
| 76 | PIK3CA | 20532 | -7.036 | -0.5104 | Yes | ||
| 77 | FBXW11 | 20554 | -7.084 | -0.5000 | Yes | ||
| 78 | PRKCE | 20653 | -7.365 | -0.4927 | Yes | ||
| 79 | MYB | 20674 | -7.418 | -0.4818 | Yes | ||
| 80 | STAT3 | 20789 | -7.787 | -0.4745 | Yes | ||
| 81 | RASA1 | 20833 | -7.927 | -0.4638 | Yes | ||
| 82 | STAM2 | 20950 | -8.362 | -0.4557 | Yes | ||
| 83 | CISH | 20981 | -8.501 | -0.4435 | Yes | ||
| 84 | RELA | 21022 | -8.671 | -0.4314 | Yes | ||
| 85 | CCND2 | 21139 | -9.105 | -0.4222 | Yes | ||
| 86 | NRAS | 21157 | -9.167 | -0.4083 | Yes | ||
| 87 | IL2RG | 21168 | -9.223 | -0.3939 | Yes | ||
| 88 | MAPK8 | 21208 | -9.408 | -0.3807 | Yes | ||
| 89 | UGCG | 21296 | -9.876 | -0.3688 | Yes | ||
| 90 | FYN | 21301 | -9.911 | -0.3531 | Yes | ||
| 91 | SOCS1 | 21356 | -10.225 | -0.3393 | Yes | ||
| 92 | ELF1 | 21369 | -10.293 | -0.3233 | Yes | ||
| 93 | BCL2 | 21371 | -10.300 | -0.3069 | Yes | ||
| 94 | FRAP1 | 21383 | -10.384 | -0.2908 | Yes | ||
| 95 | HSP90AA1 | 21420 | -10.699 | -0.2753 | Yes | ||
| 96 | RPS6KB1 | 21479 | -11.098 | -0.2602 | Yes | ||
| 97 | TNFAIP3 | 21482 | -11.148 | -0.2424 | Yes | ||
| 98 | BCL2L1 | 21524 | -11.498 | -0.2259 | Yes | ||
| 99 | DOK2 | 21579 | -12.057 | -0.2090 | Yes | ||
| 100 | STAT5B | 21655 | -13.076 | -0.1915 | Yes | ||
| 101 | STAT1 | 21656 | -13.091 | -0.1706 | Yes | ||
| 102 | PTK2B | 21693 | -13.678 | -0.1503 | Yes | ||
| 103 | TNFRSF1A | 21703 | -13.816 | -0.1286 | Yes | ||
| 104 | NFKBIA | 21775 | -15.114 | -0.1077 | Yes | ||
| 105 | LCK | 21778 | -15.166 | -0.0835 | Yes | ||
| 106 | SP1 | 21811 | -15.984 | -0.0593 | Yes | ||
| 107 | MALT1 | 21871 | -18.066 | -0.0331 | Yes | ||
| 108 | CCND3 | 21924 | -22.833 | 0.0011 | Yes |
